Two Cancer Research UK funded Post-Doc positions

We are looking to recruit a Post-Doctorate Research Associate for a fixed term period of 2 years and full time with skills in cell biophysics to work on an exciting new Cancer Research UK funded project applying mechanobiology to study cell signalling.

The interdisciplinary project aims to study the mechanical activation of cell receptors, such as Notch, using novel technology developed in the Toseland lab. This approach is based around a fusion of magnetic tweezer based assays with high throughput-screening. You will work alongside an engineer/biophysicist to further develop this technology, and use this new technique, along with biochemical and cell imaging methods to monitor the receptor activity. We will aim to use this approach to perform drug screening assays under mechanically activated states.

To enhance the chances of success on this ambitious project, we encourage applicants with prior knowledge/experience of mammalian cell culture, cell imaging, cell signalling or force-based manipulation experiments (e.g. optical or magnetic tweezers).

As Post Doctoral Research Associate you will:

Develop an independent approach to the research project in both the design and execution of the necessary experiments.

Co-supervise with Dr. Chris Toseland and the postgraduate students working on the same project.

Take the lead in preparing manuscripts for publication describing the results of the work

Help supervise other lab members e.g. MSc/PhD students technically and academically

Attend national/international conferences relevant to the research and present research findings orally or as a poster.

Manage your own research and administrative activities, with guidance if required and report on progress regularly.

To be successful in this role you will have:

Training/experience with mammalian cell culture
PhD awarded (or about to be) in a relevant subject
Detailed experience of cell imaging (confocal/widefield)
Experience of molecular biology, Image analysis and processing and single molecule microscopy (SMLM)

The School of Biosciences is a part of the University’s Faculty of Science, and teaches undergraduate degree programmes in Biochemistry, Biology and Biomedical Sciences. Research projects are also undertaken in the same disciplines. The laboratory research interests of the School include:

o Protein Science
o Molecular Microbiology
o Biomolecular Medicine
o Genome Evolution

Start date for applications: 20th February 2018

Closing date for applications: 12th March 2018

Interviews are to be held: w/c 19th March 2018

Please see the links below to view the full job description and also to apply for this post. If you require further information regarding the application process please contact The Resourcing Team on jobs@kent.ac.uk quoting ref number: STM0885

Please note – applications must be made via the University’s online application system. You will be required to fill in the main details section of the application form as well as upload your CV and a cover letter. Your cover letter should clearly and explicitly address the requirements of the Person specification and you should provide clear evidence and examples in your application which back-up any assertions you make in relation to each criterion. We recommend a maximum of 4 x A4 sides for this document.

CVs or details sent directly to the department or via email cannot be considered.
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Second position:
We are looking to recruit a Post-Doctorate Research Associate for a full time, fixed term period of 18 months, with skills in biophysics/engineering to work on an exciting new Cancer Research UK funded project to develop a new mechanobiology tool.

This is based around a fusion of magnetic tweezers with high-throughput screening. The PDRA will design and implement a system to apply a variable magnetic field across a microplate. The technology will be incorporated into imaging and microplate reader systems. The PDRA will work alongside a cell biophysicist to apply the technology to cell-based assays. We will aim to use this approach to perform drug screening assays under mechanically activated states.

To enhance the chances of success on this ambitious project, a research associate is required who has prior knowledge of designing/building magnetic tweezers, using electro-magnets or applying electromagnetic fields, and force-based manipulation experiments applied to biological systems.

As Post Doctoral research associate you will:
Develop an independent approach to the research project in both the design and execution of the necessary experiments.
Take the lead in preparing manuscripts for publication describing the results of the work
Use new techniques, methods and continually update knowledge and understanding of the field.
Help supervise other lab members e.g. MSc/PhD students technically and academically
Attend national/international conferences relevant to the research and present research findings orally or as a poster.
Manage your own research and administrative activities, with guidance if required and report on progress regularly.
To be successful in this role you will have:

Training/experience in working with Magnetic tweezers
PhD awarded (or about to be) in a relevant subject or equivalent
Detailed experience of designing/building magnetic tweezers
Training/experience with electromagnets/magnetic fields
To write up results for publication in scientific journals

The School of Biosciences is a part of the University’s Faculty of Science, and teaches undergraduate degree programmes in Biochemistry, Biology and Biomedical Sciences. Research projects are also undertaken in the same disciplines. The laboratory research interests of the School include:

o Protein Science
o Molecular Microbiology
o Biomolecular Medicine
o Genome Evolution

Start date for applications: 20th February 2018

Closing date for applications: 20th March 2018

Interviews are to be held: w/c 9th April 2018

Please see the links below to view the full job description and also to apply for this post. If you require further information regarding the application process please contact The Resourcing Team on jobs@kent.ac.uk quoting ref number: STM0886

Please note – applications must be made via the University’s online application system. You will be required to fill in the main details section of the application form as well as upload your CV and a cover letter. Your cover letter should clearly and explicitly address the requirements of the Person specification and you should provide clear evidence and examples in your application which back-up any assertions you make in relation to each criterion. We recommend a maximum of 4 x A4 sides for this document.

CVs or details sent directly to the department or via email cannot be considered.

Postdoctoral positions (Fluorescence Microscopy), University of Washington

Multiple postdoctoral positions are available immediately with Joshua Vaughan in the Department of Chemistry, whose interdisciplinary research group develops new chemical and optical tools for fluorescence microscopy for application to biological questions.
Highly motivated candidates with a background in biology, chemistry, engineering, or related disciplines are sought for two new projects: 1) An NIH-funded project focused on the development of new probes and methods for highly multiplexed probing of mRNA in cells and tissues, and 2) a non-federally supported project focused on the development of new fluorescence-based assays to read out the epigenetic state of single cells, to be used to study stem cell differentiation. Researchers will gain experience in the development of advanced methods for fluorescence microscopy (including single-molecule localization microscopy (e.g., STORM/PALM), expansion microscopy, structured-illumination microscopy) and the use of these methods to answer questions in cells and tissues. Funding is available for several years; initial appointment will be for one year, with potential renewal for one or more years if mutually agreeable.

Applicants should hold a Ph.D. in biology, chemistry, or a related discipline; significant experience in fluorescence microscopy, mRNA sequencing, epigenetics, quantitative biology, and/or optics is advantageous. To apply, email a cover letter describing your interests, a brief summary (no more than 1-2 paragraphs) of past and present research activities/accomplishments, expected date of availability, and a CV to Joshua Vaughan, and arrange for three letters of reference to be sent by email to jcv2@uw.edu; all application materials should be sent by March 14, 2018.

Michigan IRACDA Program is accepting applications

This NIH-supported program (https://iracda.umich.edu/) provides 4 years of postdoctoral funding and is targeted at fellows with strong interests in both research and teaching. IRACDA fellows spend 75% of their time doing research and 25% teaching, and the teaching is done in partnership with Henry Ford College and Wayne County Community College District in Detroit. Fellows can work with research mentors in the biosciences throughout the medical school or engineering.

Our website lists the full application requirements, but fellows must be US citizens/Permanent Residents, and have received their Ph.D. in the 12 months or will complete their thesis requirements before starting in August 2018. The application deadline is April 1, 2018.

Feel free to email me (dsept@umich.edu) if you or potential fellows from your group have questions. I will also be at the Biophysical Society Meeting next week and can provide more details in person.

Technician position in Kelly Lee’s lab at UW

This will be a 100% FTE appointment that requires expertise in cell culture, protein expression and purification, DNA cloning and site-directed mutagenesis. This position requires the ability to effectively perform research and take responsibility for assuring quality, cost-effectiveness, and timeliness for large size projects.

The successful applicant will join a research project at the interface of biochemistry, structural biology, biophysics, and vaccine design. Our work focuses on structural and functional studies of influenza virus and HIV cell entry machinery with translational applications in the development of vaccines and virus inhibitors. The research is highly interdisciplinary and collaborative, which provides the opportunity to interact with scientists from different fields. In addition, the individual will have the opportunity to gain experience in advanced mass spectrometry, electron microscopy, spectroscopy, and virology.

Main research responsibilities include:

– Implement a pipe-line for recombinant protein expression and purification (this is currently being performed by multiple people in the lab, and we seek to consolidate this into a pipeline the new scientist would run).

– Carry out mutagenesis and cloning of new constructs for protein expression

– Assess the state of the purified materials using biochemical and biophysical assays such as SDS-PAGE, native gels, electron microscopy, light scattering, etc. Training available for biophysical approaches.

– Analyze, compile and prepare data for publications and grant applications.

– General lab functions including making solutions, weighing reagents, making buffers, setting up laboratory apparatus and instructions, reading and recording instrument data, keep laboratory records, taking part in preparing results for publications, maintaining cell culture and ordering lab supplies.

– Other duties around the lab as assigned and needed.

Requirements:

Bachelors degree or higher in biochemistry or related fields, and at least 1-3 years of experience in biological research wet lab environment.

Ability to work in biological wet lab environment: make buffers and solutions, express and purify proteins; keep lab records and experiment notebook. Experience running SDS-PAGE, gel filtration and ion-exchange chromatography, ELISA and related biochemical assays.

Assistant Professor position at Cal State Univ. Los Angeles

CSULA is a comprehensive urban university located east of Downtown Los Angeles with an enrollment of approximately 28,000 students representing one of the most diverse populations in the country. The Department of Chemistry & Biochemistry offers B.S. degrees in Chemistry and Biochemistry and an M.S. degree in Chemistry with the optional emphasis in Biochemistry. The Department hosts more than undergraduate 800 majors and approximately 50 Master’s students. The Department has a strong tradition and commitment to research success involving undergraduate and Master’s students, and its 16 full-time faculty are active in teaching and research with an ethnically and socioeconomically diverse student population. We invite interested candidates to apply for this position in Theoretical/Computational Chemistry by the Nov. 27, 2017 deadline.

http://www.calstatela.edu/2018/college-natural-social-sciences/nss-cb-ttf2

TT position in the Department of Physics, University of Alberta

The Department of Physics, University of Alberta (www.physics.ualberta.ca)
invites applications for a tenure-track faculty position in either
experimental or theoretical biophysics. We primarily seek candidates at the
Assistant Professor level, but exceptional candidates at a more senior
level may be considered. Applicants must possess a Ph.D. in physics,
biophysics, or an appropriately related field and have an excellent
research record. The successful candidate will be expected to develop and
maintain an internationally recognized independent research program. As a
faculty member in the Department of Physics, the successful applicant is
expected to obtain external funding, participate in departmental
activities, mentor graduate students, and contribute to our educational
responsibilities by effectively teaching undergraduate and graduate courses.

The Department of Physics has 48 faculty with research interests in
condensed matter physics, astrophysics, space physics, geophysics, particle
physics and biophysics. Access to a wide range of infrastructure for
biophysical research is available on campus, from laser spectroscopy labs
and microscopy facilities to structural and chemical characterization labs,
nano-fabrication facilities, molecular biology services, clusters for
high-performance computation, and the Peter S. Allen Magnetic Resonance
Centre. An extensive medical research and hospital complex at the
University of Alberta offers many opportunities for interdisciplinary
collaboration, as does the Nanotechnology Initiative with the National
Research Council. Initiatives by the Governments of Alberta and Canada
provide exceptional opportunities for additional funding to establish new
research programs at the University of Alberta. For example, several of our
professors hold Alberta Innovates Technology Futures (AITF) Chairs.

To apply, please:

1) Click APPLY ONLINE
to submit a
CV, a list of publications, a statement of research interests, and a
summary of teaching interests (submit as one document).
2) Arrange for at least 3 referees to email confidential reference letters
directly to: Suzette Chan , referencing Subject:
Biophysics Competition #A107833883.

The referees should address their letters to:

The Selection Committee
Department of Physics
University of Alberta
Edmonton AB
Canada, T6G 2E1

To assist the University in complying with mandatory reporting requirements
of the *Immigration and Refugee Protection Act* (R203(3) (e)), please
include the first digit of your Canadian Social Insurance Number in your
application. If you do not have a Canadian Social Insurance Number, please
indicate this in your application.

Applicant evaluation will begin on November 15, 2017. The anticipated start
date is July 1, 2018.
How to Apply

*Apply Online*

*Note:* Online applications are accepted until midnight Mountain Standard
Time of the closing date.

All qualified candidates are encouraged to apply; however, Canadians and
permanent residents will be given priority. If suitable Canadian citizens
or permanent residents cannot be found, other individuals will be
considered.

The University of Alberta is committed to an equitable, diverse, and
inclusive workforce. We welcome applications from all qualified persons. We
encourage women; First Nations, Métis and Inuit persons; members of visible
minority groups; persons with disabilities; persons of any sexual
orientation or gender identity and expression; and all those who may
contribute to the further diversification of ideas and the University to
apply.

Faculty positions in Applied Physical Sciences at UNC-CH

The Department of Applied Physical Sciences (APS) at the University of North Carolina at Chapel Hill invites applications for three tenure-track or tenured faculty positions. The goal of APS is to bridge fundamental research and training in the science and engineering of materials with translational impact on society’s most challenging problems.  APS partners with all STEM and Health Affairs departments toward multidisciplinary, team-based research, education, and entrepreneurship in a top 10 public research university.  This hiring initiative continues an aggressive strategy to build a pre-eminent Department of Applied Physical Sciences, aiming for 20 new hires together with joint appointments from partnering departments.  These new positions are intended to build upon existing strengths and aim for international prominence and leadership in the science and engineering of materials at the intersection of the physical, life, and energy sciences.  
 
All candidates should have clear potential, and commitment for research excellence, multidisciplinary collaboration, extramural funding from government, industry, or other sources, and translational impact in education and entrepreneurship. Excellence and commitment to education and mentorship at the graduate and undergraduate levels are essential qualities for these recruitments.  The Department and the University of North Carolina at Chapel Hill are broadly committed to equity and inclusion.  It is part of our institutional mission to teach and engage a diverse community of undergraduate and graduate students, and postdoctoral scholars.  We especially welcome applications from candidates who are committed to advancing these ideals.  A PhD in a STEM  field (science, technology, engineering or math) or related fields that contribute to applied physical sciences, is required.   
 
Applications will only be accepted online (https://unc.peopleadmin.com/postings/128403). Applicants should submit a curriculum vitae, a research statement, a statement on teaching and mentorship, and 1-2 representative publications (optional). Applicants are required to identify the names, titles, email addresses and phone numbers of four professional references when applying. Reference providers identified by the applicant will be contacted via email with instructions for uploading their letters of support. Review of fully completed applications will begin October 15, 2017. Positions are open until filled. Questions should be directed to: Chair, Applied Physical Sciences Search Committee, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3050, apssearch@unc.edu.
 
The University of North Carolina at Chapel Hill is an equal opportunity employer that welcomes all to apply, including protected veterans and individuals with disabilities.

TT Assistant or Associate Prof. position at George Washington University (Analytical Chemistry)

The Department of Chemistry at the George Washington University invites applications for a tenure-track Assistant or Associate Professor of Chemistry beginning as early as Fall 2018 in Analytical Chemistry. The search, which is pending final budgetary approval, is open to all areas of analytical chemistry, including those with application to separations with particular focus on biomolecules or sensors for use in energy/environmental needs or homeland security and that complement the existing strengths of the department. Assistant Professor candidates are expected to develop a highly active, funded research program. Candidates at the Associate Professor level are expected to demonstrate a substantial record of scholarly achievement and national reputation in the field of their specialty. The successful candidate is expected to advance the vision of the University and the Department as a leading global research University. The successful candidate is expected to demonstrate commitment to excellence in teaching at the graduate and undergraduate level.
In addition to offering B.S., M.S. and Ph.D. degrees in Chemistry, our dynamic faculty of 17 has cooperative programs with the George Washington University Medical Center (The Cancer Institute [https://smhs.gwu.edu/katzencancer] and Neuroscience), Biological Sciences (The Institute for Proteomics Technology and Applications and Bioinformatics), and Engineering and Physics (an Institute for Materials Science and Institute for Nanotechnology). Furthermore, under the leadership of the Vice President for Research, the University has created several more prominent Research Institutes. In January 2015 the Department moved into a newly constructed 250,000 ft2 Science and Engineering Hall, containing a state-of-the-art imaging suite and nanofabrication/cleanroom facility (https://nic.gwu.edu). The imaging instrumentation includes new SEM, TEM, FIB-SEM and Confocal Microscopes. A number of prestigious research laboratories, such as the National Institutes of Health, Naval Research Laboratory, Children’s National Medical Center, National Institute of Standards and Technology, and the Food and Drug Administration, all in the area, also provide unique opportunities for cooperative research programs. The University is located in downtown Washington, D.C. within a few blocks of many important institutions.
Basic Qualifications for Assistant Rank: Applicants must have a Ph.D. or Doctoral degree in Chemistry or a related field.
Basic Qualifications for Associate Rank: Applicants must have a Ph.D. or Doctoral degree in Chemistry or a related field. Applicants must also possess active funding.
Application Procedure for Assistant Rank: Please complete an online faculty application at https://www.gwu.jobs/postings/46504 and upload a cover letter, curriculum vita, publication list, and statements of research and teaching interests. Recommendations from at least three references should be sent by the references to chemsearch@gwu.edu.
Application Procedure for Associate Rank: Please complete an online faculty application at https://www.gwu.jobs/postings/46857 and upload a cover letter, curriculum vita, publication list, and statements of research and teaching interests. Recommendations from at least three references should be sent by the references to chemsearch@gwu.edu.

Review of Applications will begin Nov. 3, 2017.

Opening for postdoc to study biophysics of bacterial biofilms

I have an open postdoc position in my group to study impact of physical, primarily mechanical, factors in the growth and robustness of bacterial biofilms.  I have NIH and NSF funding to support such a position for up to three years, beginning as soon as possible.  I am looking for candidates with a background in soft-matter physics, chemical engineering, materials science, or similar.  Prior biological work, in particular with bacteria, is desirable but not strictly required.  Good written and oral communication skills and a strong track record of teamwork are essential – any type of multidisciplinary teamwork will be regarded very favorably.  A history of successful mentoring of younger students (undergraduate and/or graduate) will also be regarded very favorably.

Biofilms strongly impact medicine, industry, and built infrastructure.  The harms caused by biofilms are widely thought to be linked to the physical properties of biofilms, but very few specifics are known.  Therefore, biophysical studies of biofilms are a growth area, and this postdoc position has good potential to produce high-impact publications and to serve as a stepping-stone to a successful academic or industrial career.  Previous postdocs and PhD students in my group have gone on to both academic and industry positions.  A list of publications from my group is available here:  http://chaos.utexas.edu/people/faculty/vernita-gordon/gordon-publications.

I am affiliated with both the Center for Nonlinear Dynamics, in the Department of Physics, and the Institute for Cellular and Molecular Biology at UT Austin.  As a result, my lab is a dynamic, multidisciplinary research environment.  Opportunities for collaboration and initiative abound.  Austin is a thriving, rapidly-growing city with vibrant arts scenes and opportunities for outdoor recreation.

If you would like to be considered for this postdoc, please send me your CV and a brief statement of what attracts you to this position.  Please arrange to have at least three letters of reference sent to me.  My email address is gordon@chaos.utexas.edu.  If you would like to discuss this position before applying in full, please feel free to email me as well.

University of Oregon: Faculty search in Biochemistry & Experimental Physical Chemistry

The University of Oregon is conducting faculty searches in biochemistry and experimental physical chemistry, to start in Fall 2018 or later. A Ph.D. degree is required. Successful candidates will have the potential for establishing an outstanding independent research program, maintain excellence in teaching at the undergraduate and graduate levels, and support and enhance a diverse learning and working environment. Biochemistry: Applications are invited for a tenure-track position in biochemistry at the Assistant Professor level. Biochemistry research takes place in the context of the Institute of Molecular Biology, which promotes interdisciplinary interactions between life science researchers in the departments of Chemistry & Biochemistry, Biology, and Physics. We seek applicants from all areas of biochemistry and structural biology who use advanced approaches to study mechanisms of cellular function. See the online posting for details and application instructions. To assure full consideration, application materials should be received by October 9, 2017; review of application materials will continue until the position is filled. Experimental Physical Chemistry: Applications are invited for a tenure-related position in experimental physical chemistry, expected at the Assistant Professor level (though exceptional candidates in theoretical chemistry or at more advanced ranks will be considered). We seek individuals studying problems of fundamental importance to experimental physical chemistry, which may also be applied uniquely to advance related chemical disciplines; of particular interest are scholars who will enhance existing departmental strengths in biophysical chemistry, materials related physical chemistry, spectroscopy, statistical mechanics and quantum chemistry. Postdoctoral experience is preferred. The successful candidate will have the opportunity to pursue research in a variety of interdisciplinary institutes. See the online posting for details and application instructions. To assure full consideration, candidates should submit application materials by October 3, 2017; the position will remain open until filled.

The online posting can be found here: https://academicjobsonline.org/ajo/jobs/9374